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July 12, 2025 in Kidney Stone

Urinary System

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URINARY SYSTEM

 It has 5 parts
  •  Kidney
  •  Ureter
  •  Urinary Bladder
  •  Urethra
  •  Prostrate

urinary
FUNCTIONS OF KIDNEY

Our kidneys are the important part of our excretory system. Its primary function is :-
4. Regulation of water and electrolytes in body(sodium, potassium, calcium) .
2. Excretion of waste products of metabolism
3. Regulation of the acid-base homeostasis of blood
4. Excretion of drugs,.chemical and toxins

FUNCTION OF URINARY BLADDER

It is a muscular structure and storage organ for urine received from both kidneys. It is continue as urethra, at the bladder neck urethra
surrounded by prostrate gland. Normal prostrate size is necessary for smooth outflow of urine.

IMIPORTANT DISEASES OF URINARY SYSTEM

  1. Urinary stone
  2. Urinary Tract Infection (UTI)
  3. Enlarged prostate-benign prostratic hyperplasia (BPH)
URINARY STONE

It is an excruciating painful condition often described as one of the strongest pain sensation.

  1.  3rd most common affliction of the urinary tract after UTI and BPH
  2.  In India more than 150 million people experienced stone’s pain once or multiple times in their life
  3.  Mainly disease of young and middle age
  4.  50% of patients experience recurrent stone formation within 5 years
  5.  Although more common in males but almost equally affects females
  6.  Most of the stone disease can be treated with medicine and diet modification

TYPE OF STONES

  1.  Calcium stone (most common)
  2.  Uric acid stone (less than 5%)
  3.  Struvite stone (MAP stone)
  4.  Cystine stone
SYMPTOMS OF STONE
  1.  Pain-sharp, severe, acute colicky pain starting from flank (back) and radiate to lower abdomen or genitalia. OR Dull aching pain at back
  2.  Hematuria (blood in urine)
  3.  Nausea and vomiting
  4.  Persistent urine burning
  5.  Fever if stone causes obstruction and infection
  6.  Cloudy or foul-smelling urine
  7.  Painful urination or inability to pass urine
stone type
PROCESS OF STONE FORMATION

Renal stones are the polycrystalline aggregates composed of varying amount of crystalloid and organic matrix.

Stone formation requires super saturated and stagnant urine. Saturation of urine is decided by. PH of urine, ionic (calcium, oxalate, uric acid,
phosphate, sodium) concentration in urine and concentration of natural stone inhibitors (citrate, magnesium, sulfate)in urine. Stagnation of urine occurs in obstruction of outflow from kidney, in voiding dysfunction, in enlarged prostrate.

Stone formation occurs when PH of urine get disturbed, urinary flow get disturbed, ionic concentration increased in urine so solubility of urine
decreases and crystal formation starts.

Multiple steps are involved in crystal formation like Nucleation, growth, aggregation. A crystal of one type promotes growth of other type of
crystal, Ultimately these crystals form large stone incapable of passing.

RISK FACTORS OF STONE FORMATION
  1. Increased crystal concentration in urine
    1. Increased intake of calcium and sodium
    2. Bowel disorders and metabolic disorders
    3. Increased intake of purines
    4. Gout, malignant conditions
    5. Inborn errors
    6. High intake of meat and dairy products
    7. Sudden weight loss
  2. Low fluid intake
  3. Stasis of urine flow
  4. Long term foreign body like catheter, DJ stent
  5. Hot and dry climate
  6. Family history of stone
  7. Industrialization
  8. Physical inactivity
  9. Recurrent non-specific UTI
stones
AIM OF TREATMENT
  1. To get relief from stone pain
  2. To reduce the chances of recurrent stone formation
  3. To reduce the need of surgery
  4. To get relief from blood in urine, urinary burning
  5. To improve quality of life of a stone sufferer
HOW TO ACHIEVE OUR GOAL (RECURRENT STONE TO NO STONE)
  1. By making the urine under saturated, more soluble
  2. By maintaining hydration of kidney
  3. By preventing stasis of urine
  4. By preventing formation of large obstructing crystals
  5. By decreasing concentration of ions in urine
  6. By increasing concentration of stone inhibitors
  7. By decreasing intake of meat, dairy product, calcium supplements, high salt, purines
  8. By encouraging fluid intake
  9. By avoiding long term foreign body
  10. By encouraging physical activity
  11. By preventing recurrent UTI
  12. By prophylactic treatment for recurrent stone formation
MECHANISM TO ACHIEVE GOAL BY MEDICAL TREATMENT

Any medicine which

  1. Discourages crystal formation and causes disintegration and fragmentation of crystals
  2. Causes early expulsion of small stones
  3. Decreases the ionic excretion
  4. Increases stone inhibitors in urine
  5. Treats UTI at same time
  6. Causes diuresis to make urine under saturated
  7. Improves outflow of urine
  8. Makes urine more soluble
  9. Most of the stones occur in acidic urine so makes urine alkaline
  10. Prevents recurrent stone formation by inhibiting initial crystal deposition and subsequent growth of stone and by correcting crystalloid-colloid imbalance
ROLE OF UREPRO KIT (RECURRENT STONE TO NO STONE)

Our motive — Healthy kidney with pain free life for all for corrective and preventive management of stone inhibitor, stone smasher, stone flusher Since last 22 years we are serving humanity

  1. Urepro kit has permissive role in corrective and preventive management of urinary stone exerts double strength at same time.
  2. Urepro kit is one of the most trusted and tested brands for renal (urinary) stone provides non-surgical option and hospitalization is not required during treatment.
  3. Urepro kit is a safe, herbal formulation having different vital herbs in an appropriate combination.
  4. Urepro kit is most effective, affordable, fast acting, palatable medicine for urinary stone without any side effects.
  5. Urepro kit therapy is very convenient and can be taken during your daily work routine.
  6. Because of complexity of renal stone multiple doses of urepro kit can be taken decreased PH of urine, stasis of urine and dehydration leads to urinary minerals calcium, phosphate, oxalate, uric acid to get deposited as renal
    stone. Urepro kit is a potent litholytic, anti-microbial, diuretic and alkaliser which makes it a stone inhibitor, stone smasher, stone flusher, apart from this it prevents recurrence of stone formation.
Urepro kit acts by
  1. Anti-lithogenic and anti-calcifying property
  2. Stone disintegration and litholytic property
  3. PH regulation
  4. Diuretic action
  5. Anti-microbial action
  6. Anti-inflammatory property
  7. Increasing concentration of stone inhibitors
  8. Making urine more soluble by its alkalinizing property
  9. Nephro- protective
  10. Improving tone of musculature
  11. Improving outflow
  12. Making urine unfavorable for micro-organism growth
urepro kit poster
BENEFITS OF UREPRO KIT
  1. Relives pain of urinary stone
  2. Relives symptoms of UTI
  3. Improves kidney function
  4. Prevents recurrence of urinary stone and UTI
INDICATIONS OF UREPRO KIT
  1. Urinary calculi
  2. Recurrent urinary calculi
  3. Non-specific UTI
  4. Dysuria and burning micturation
SAFETY PROFILE OF UREPRO KIT

It is a completely safe herbal medicine

ADVERSE EFFECTS OF UREPRO KIT

No known side effects

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